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Loss of oxygen to cells - how does this work?

Human Anatomy, Physiology, and Medicine. Anything human!

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Loss of oxygen to cells - how does this work?

Postby gabyabbi28 » Tue Nov 03, 2009 8:39 pm

This is a general query, as a friend and i had been discussing it but then realised that neither of us actually knew..

So, if you tied some string tightly around the end of your finger or a toe, or your nose, and left it for days, this would cut off the flow of oxygen to that part of your body and it would die, yes? But then what would happen? Would it just fall off? If it did, would the area when it came from bleed? Or if you took the string off would it come back to life?

Also, if you continued to tighten the string, would it tighten around your finger until the string eventually touched the bone/the other side of the string, therefore just being a not with a tiny strip of skin between it, separating the end of the finger from the rest of your hand?

Please answer if you actually KNOW the answer and arn't just guessing, as replies will settle this grueling debate. An in depth, accruate analysis would be greatly appreciated.

Thanks.
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Postby JackBean » Tue Nov 03, 2009 11:08 pm

OK, I wished to answer, but due to the last paragraph... :roll: do you really think, that someone here has experiences with finger tightening? I hope no...

Anyway, if tighten the finger, you will minimize the blood flow (don't think, that completely stop), so the level of oxygen and other nutrients will decrese and level of metabolites will increse, what will lead to dead.
If you began to rescue someone, who is dead for some time already, do you think, s/he would live again? :roll:
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Postby TheVirus » Wed Nov 04, 2009 3:33 am

If you tighten the string hard enough and long enough, as JackBean said, the level of oxygen and other nutrients will decrese and level of metabolites will increse, what will lead to death. If you keep tightening it for months (or weeks, assuming that you let the rats and bugs eat your rotting finger off), yes, it would eventually be so gangrenous that i will fall off, and it will bleed little to nothing. And yes, if you go on, your finger will be so not like a finger that the string will be able to pass trough it to the bone (but not through the bone, obviously).
All this is true, but you need to bear in mind that the kind of pain you'd feel while doing this (on account of the whole rotting, nerves dying, your finger turning into dirt) would be so unbereable that no person would be able to do it, unless they can't feel pain (or like pain, who knows?). Plus, the risk of getting an infection while doing this trick is very high (since you leave your whole finger open for bacteria, fungi, etc). You'd get a fever, and if untreated, you go delirious and die before your act is finished.
Oh, yeah, one more thing, if you suddenly decide to loosen the string, the amount of tissue that could be saved from your finger depends on when you do it (if its too late, they may need to amputate your whole finger or hand, unless it's aleady fallen off on its own).
”It is not the strongest of the species that survives, nor the most intelligent that survives. It is the one that is the most adaptable to change.”
~Charles Darwin
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Postby gabyabbi28 » Mon Nov 09, 2009 2:34 pm

YESS!! I was right. Thank you all.
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Postby TheVirus » Tue Nov 10, 2009 12:59 am

Glad for you. You're welcome.
”It is not the strongest of the species that survives, nor the most intelligent that survives. It is the one that is the most adaptable to change.”
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