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dna architecture and chelates

Discussion of all aspects of biological molecules, biochemical processes and laboratory procedures in the field.

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dna architecture and chelates

Postby choozi » Sat Oct 10, 2009 12:06 pm

what is DNA architecture? and what sort of chelate are involved in DNA? can anyone tell me the links regarding this information? plz..
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Postby JackBean » Sat Oct 10, 2009 12:16 pm

I would guess www.google.com or www.pubmed.com ;)

What about phosphate? Also the bases could have some chelating proparties, but not sure, about that
http://www.biolib.cz/en/main/

Cis or trans? That's what matters.
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Postby kolean » Sun Oct 11, 2009 3:28 am

Chelation usually involves a metal ion (like Ca2+, Fe2+/3+, Mg2+, or even Cu2+), but there is no metal ions involved with DNA and its architecture. It uses pretty much proteins to build its architechure with nucleosomes composed of histones (H2A and H2B, H3, and H4) to form a beads on a string structure. And then the linker histone H1 to form a 30 nm fiber of coiled beads into a rope structure. From there, it can have chromatin modeling protein complexes to make it into heterchromatin (condensed and repressed transcriptionally) or euchromatin (maybe a loose scaffold of DNA and proteins for active transcription).
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