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si-Fi, Software for RNAi off-target predictionModerator: BioTeam
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si-Fi, Software for RNAi off-target predictionHello!
I’m pleased to announce si-Fi 1.2beta - our new Software for RNAi (RNA interference) off-target prediction. The software is designed for checking long-double stranded RNAi constructs for target specificity and silencing efficiency. It can be used also for selecting sequences regions suitable for designing RNAi constructs for specific and efficient silencing of genes. The program provides clear tabular and graphical outputs. Simply paste your RNAi trigger sequence and check it for targets and off-targets within your local sequence database (unigene sets for many species can be downloaded free of charge from the specialized online databases). Unlike the online tools, si-Fi uses a local sequence database that gives you a full control over it. Any sequence database in a multiple Fasta format can be imported with few mouse clicks only. You are kindly invited to test the Beta version of si-Fi by downloading it from: http://www.snowflake-sl.info/sifi.htm This is open source software which can be considered as a gift to the community. It can be used and distributed free of charge. Any comments and suggestions are welcome. Please sent it to mail@snowflake-sl.info Kind regards Stefanie www.snowflake-sl.info
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