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DNA

Genetics as it applies to evolution, molecular biology, and medical aspects.

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DNA

Postby kareliagarcia76 » Wed Sep 30, 2009 12:20 am

What are the mechanisms by which DNA is packaged into the nucleus and organized in such a way that it does not get ripped apart during cell division?
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Postby mith » Wed Sep 30, 2009 1:50 am

shouldn't the dna be ripped apart during division?
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Re:

Postby kareliagarcia76 » Wed Sep 30, 2009 1:56 am

I'm not sure. I'm thinking that its because it replicates itself rather than ripping apart.
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Postby choozi » Thu Oct 01, 2009 3:55 pm

DNA coil and supercoil and rotate around histone proteins to form nucleosomes.
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Postby kolean » Thu Oct 01, 2009 11:03 pm

I would say it is more like unzipped apart than ripped apart. And with all the proteins surrounding the DNA, it is more delicate than the word ripped conveys. More likely seduced apart by attracting forces........lol.

Nucleosomes are the octamer of histones that the DNA wraps itself around 2 1/2 times around, with a linker DNA between these "beads". This "beads on a string" is then coiled into a 30 nm fiber with Histone 1 linking them together. This fiber can then be condensed into another fiber that may be modeled with chromatin proteins into heterochromatin, which is usually visually observed at the telomeres and at the centromeric regions. Chromosomes are then attached to the nuclear plasma membrane as an anchorage site.
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