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Review: PPMO and Vivo-Morpholinos

Genetics as it applies to evolution, molecular biology, and medical aspects.

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Review: PPMO and Vivo-Morpholinos

Postby jonmoulton » Wed Mar 25, 2009 10:58 pm

Conjugation of Morpholino oligos with endosomal escape moieties is bringing effective antisense techniques to rodent research. Such conjugates will likely debut soon as therapeutics. This is an open-access review of two delivery-enabled forms of Morpholinos.

Moulton JD, Jiang S. Gene Knockdowns in Adult Animals: PPMOs and Vivo-Morpholinos. Molecules. 2009; 14(3):1304-1323.

It's always satisfying to finish a paper. :)
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Postby MrMistery » Thu Mar 26, 2009 2:03 am

good read. and free access, for those with no institutional logins.
"As a biologist, I firmly believe that when you're dead, you're dead. Except for what you live behind in history. That's the only afterlife" - J. Craig Venter
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