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How is mitochondria involved in regulating calcium???

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How is mitochondria involved in regulating calcium???

Postby sundew773 » Sun Jun 26, 2005 12:00 am

I can't find how mitochondria is involved in regulating calcium anywhere :(

So far we've discussed that mitochondria is involved with apoptosis, the proton motive force, and ATP synthase...does calcium fit in somewhere?

Much thanks! :D
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Postby MrMistery » Sun Jun 26, 2005 8:35 pm

Calcium is poison to the cell. Ca2+ ion has the highest gradient in the human body: it is 40000 times more outside the cell than inside. In extreme conditions, when there is too much Ca2+ in the cell, the mithocondria can accept Ca2+ ions. There are 4 transporters located on the membrane of the mithocondria for this purpose.
Nice question, it put my memory to work... :D :D
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Postby sundew773 » Sun Jun 26, 2005 9:23 pm

MrMistery wrote:Calcium is poison to the cell. Ca2+ ion has the highest gradient in the human body: it is 40000 times more outside the cell than inside. In extreme conditions, when there is too much Ca2+ in the cell, the mithocondria can accept Ca2+ ions. There are 4 transporters located on the membrane of the mithocondria for this purpose.
Nice question, it put my memory to work... :D :D


Thanks so much, that makes perfect sense! :)
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Postby MrMistery » Sun Jun 26, 2005 9:28 pm

Everything makes sense in biology, that's why it is so fun 8)
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Postby LrdGeno » Mon Jun 27, 2005 3:35 pm

Isn't there something called a calcium - potassium pump? I think that's what it's called anyhow, and if that is the name I have no idea where it is in the body
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Postby mith » Mon Jun 27, 2005 4:05 pm

There's a sodium potassium pump
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Postby Poison » Mon Jun 27, 2005 4:33 pm

Nerve cells use Na-K pump.
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Postby MrMistery » Mon Jun 27, 2005 8:10 pm

Actually all cells have NA/K pumps. It's only that nerve cells use it all the time, they have much more of them. Actually 70% of the energy used by the neuron is used by the Na/K pump.
And no, there is no such thing as a calcium potasium pump.
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