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Two models of Enzyme-Substrate binding

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Two models of Enzyme-Substrate binding

Postby shobber » Mon Jun 16, 2008 4:47 pm

Here is a question: What's the merit of the "Induced-fit model" over the "Lock and Key model" regarding enzyme and substrate binding?
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Postby mith » Mon Jun 16, 2008 6:17 pm

lock and key assumes substrate/enzyme are rigid. That means it's easier to calculate docking if you're doing it computationally.
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Postby MrMistery » Mon Jun 23, 2008 5:26 pm

induced fit is more close to reality. if you're learning it theoretically, it's the "right" one.
lock and key is a reduction, but it is easier to work with.
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