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Erythrocytes, cell of not?

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Erythrocytes, cell of not?

Postby victor » Sun May 15, 2005 12:47 pm

Most of the cells is categoried because they do have the same important organel which is very important to replicates their own chromosomes. This organel is called nucleus. Anyway, erythrocytes' shape is biconcave and it doesn't have any nucleus. Is it still categoried as cells? or some kinda proteins? :?
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Postby Poison » Sun May 15, 2005 2:16 pm

RBC lose their nucleus when they become mature. They have nucleus when they are produced. So, yes, they are cells.
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Postby MrMistery » Sun May 15, 2005 6:00 pm

Onthogeny repeats philogeny. Red blood cells at every other vertebrate than mamals has a nucleus when they are mature. The red blood cell of o mamal, as poison said, loses it's nucleus when it is mature, in order to transport a greater amount of oxygen. SO, YES, they are cells
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Hmm....makes me wondering...

Postby victor » Mon May 16, 2005 6:13 am

:shock: Wow..that sounds great...Maybe that makes the differences between erythrocytes and lymphocytes..thanks 8)
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Postby Dr.Stein » Tue Jul 12, 2005 9:36 am

Yes, lymphocyte is leucocyte and erythrocyte is erythrocyte :wink:
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Postby victor » Tue Jul 12, 2005 1:07 pm

No, I mean that mature RBC doesn't have Nucleus but mature WBC have it..
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Postby chemistry_freako » Tue Jul 12, 2005 3:12 pm

Oo just did something related to this during one of today's lecture
RBCs (erythrocytes) lack mitochondria, nucleus, and ribosomes;
advantages of biconcave shape include increased surface area for carrying oxygen in the bloodstream, can form stacks, and can bend and flex.

In the beginning (hemopoiesis - erythropoiesis), a hemopoetic stem cell differentiates into a proerythroblast, and steps which follow are those in which the RBCs still have a nucleus. When it becomes a reticulocyte, it loses its nucleus, and becomes what it looks like - biconcave disks without nucleus.

White blood cells also include cells like neutrophils, eosinophils, basohpils, monocytes as well as lymphocytes. To understand why mature WBCs have a nucleus, but not so for mature RBCs, we can look at their functions - compare RBCs which carry oxygen in our bloodstream, with the function of lymphocytes which are generally to do with cell, and antibody related immunity.
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Postby James » Tue Jul 12, 2005 3:22 pm

So when the first organism to have red blood cells came into existance, did the RBCs have a permanent nucleus, which has since evolved to lose this for more O2 transport?
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Postby chemistry_freako » Wed Jul 13, 2005 3:42 pm

First organisms to have red blood cells? =\
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Postby Dr.Stein » Thu Jul 14, 2005 6:58 am

victor wrote:No, I mean that mature RBC doesn't have Nucleus but mature WBC have it..

Only mammals' erythrocytes that lack of nucleus and organelles. Other vertebrates have erythocytes with nucleus.
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Postby victor » Thu Jul 14, 2005 11:59 am

Actually our RBC's nucleus is pressured down because of Hb macromolecule chain...in order to gain as much Hb, they need to compress down the nucleus..
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Postby Dr.Stein » Fri Jul 15, 2005 2:12 am

Yes and because they do not need the nucleus anymore. They just need a pocket to save oxygene, so... get out nucleus and welcome oxygene! :wink:
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