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Immortality? Possibility?

Genetics as it applies to evolution, molecular biology, and medical aspects.

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Postby ahyeek » Thu Feb 15, 2007 6:38 am

For today technology and what human can imagine, i would say we can have computer + AI algorithm to actually help us to have an immortal human.

Using CCTV to capture human face expression, using NLP technology to capture and process the language and meaning, get computer AI to learn the respond and react of a person.

So, the AI algorithm in a computer will actually 'copy' a alive human brain in a electronic format + the way the person think and analysis. When the person die, the computer system can actually regenerate the person face with expression and react based on what it learned.

By using 3D or hologram technology, we can have the person model in space and actually talk to us.

I am actually searching from the web to see any PHD research on this. :)

This I would say within 20 to 30 years, perhaps human can adchieve this.

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Postby Martian » Thu Feb 22, 2007 5:46 am

Are you saying that we can be replaced by AI? Because, if I become a virtual program (algorithm), then do I still exist? A computer can simulate my personality, but I don't think I can still experience life in that form. I think a person would be dead in this case.
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Postby ahyeek » Mon Feb 26, 2007 1:34 am

Yeah, true. The person will be dead.

This is only allow the others (like your family member, friends or wife still think you are alive.

In fact, perhaps 1 day, system can capture your existing memories into a computer system and make you feel exactly in a virtual world. (The movie called Matrix already explain in quite detail of this.)

The one I suggest is not that advance yet and just only can let our beloved one still able to feel our existence.

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Postby mith » Mon Feb 26, 2007 6:46 am

I saw that in a batman beyond episode
Living one day at a time;
Enjoying one moment at a time;
Accepting hardships as the pathway to peace;
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Postby Fozu » Wed Mar 07, 2007 12:52 pm

i believe in immortal. "佛主" is an immortal.
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Postby mehdi71000 » Wed Mar 07, 2007 1:05 pm

ok maybi this is the way
every cell has in its an internal clock in its genes wich regulates the cell time that cell dies. how ever cancer is imortal cells, there clock has been turned off some how and they dont die and they keep growing. let me tell you some thing though . we are chemichal being every movement in our body is a result of chemichal reactions. chemichals dont get old. the hydrogen in your body is maby billions of years old. but its in our genes that we are designed to get old. if you can find this proseess in genes that stops some sells to function as well as in youthfull years. you can make humans imortal i think. but the question remains why are we designed to die? :shock:
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Postby Caspase » Mon Mar 12, 2007 1:06 pm

This seems silly because we cant defeat genetic error rate. So even if cancer becomes manageable over a long enough time span we will have a completely different genetic code. So I guess this is impossible until we can successfully restructure the genetic code of an adult at any time we wish.
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Re: Immortality? Possibility?

Postby blueblackhusky » Fri Mar 26, 2010 8:02 pm

Hello to all of you!

If the question was really intended from a scientific/genetic point of view, and not a phylosophical one as this discussion seems to have developed, then I am happy to try to help out.

I think that probably what you all have somehow heard of to produce these ideas about the possibility of immortality is telomerase (if I am not mistaken, the research for which the Nobel prize was awarded last year).

Telomerase, as the word's ending "-ase" suggests, is an enzyme present in eukaryote cells. It is a reverse transcriptase. Usually, transcriptases transcribe ("write off") information from a DNA molecule to a RNA molecule, in the transcription phase of protein biosynthesis. Now, telomerase is called a reverse transcriptase because it does things the other way around - it transcribes information from an RNA to a DNA. This is used to fix a problem in the replication process in the cell, namely that of chromosomes having telomeres (the ends that are made of mostly repetitive sequences with no actual value but the protection of the actual genetic information on the chromosome from various enzymes in the cell). Problems occur because very often polymerases, the enzymes that build the new DNA strand when copying, detach themselves too soon from the old strand, or even before reaching the telomere. So, the new DNA strand has less protective repetitive DNA, which decreases after every copied generation, and ultimately, there will be a DNA with no protective ends, so enzymes will start gnawing on that good, relevant coding sequences the cell needs in order to function normally and not grow senescent at a very fast pace. This is where telomerase acts up: through its structure it can build new protective sequences at the end of the chromosome and thus protect it from being degraded.

It has been found to be highly active in embryonic cells (stem cells) and cancer cells, both of which have an unlimited division potential and are thus said to be "eternal", with no definite apoptosis ("programmed cell death", or an internal clock like mehdi71000 put it) like most cells have. But in most cells telomerase grows inactive, so scientists think that maybe by reactivating it in fully grown somatic cells they might be able to stop aging and assure us immortality.

Still, it remains a very controversial subject, because degradations at chromosome ends are definitely not the only mutation-generating factors for the DNA, so we probably still would get sick, and to think we could prevent/correct any mutation is very, very farfetched, especially since we all have unique DNA sequences, no matter how much alike they are. So, at this point, with "official knowledge" this is not possible, but who knows? maybe in the future we'll invent an automation for sequencing every person's genome fast and cheap, and have enough specialists to interpret that for every person...perhaps like a gene doctor. But the complexity would still be mind-blowing. Plus, like someone said before, if you get your head chopped off, those flawless sequences are really not going to help you out :lol: .

Hope this helps.
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Postby simpleton » Sat Mar 27, 2010 3:12 am

yeah, blueblackhusky is right.

I saw in the news quite sometimes back where groups of scientists are working on telomere and how to use it to lengthen lives. I guess, with the available info we had for now, telomeres seem to be the key to immortal cells where the cells can replicate for more times. It's a biological clock which shorten after every cell cycle and as mentioned, the reason why cancer cells can keep proliferating is because they have exceptionally long telomeres.

But in my opinions, telomeres alone are not sufficient to ensure immortal cells. The key is how we can ensure accuracy in the replication of immortal cells otherwise, we will all be mutants. Haha! And it's very important to have the ability to replace mutated cells with embryonic stem cells. Then again, there limitation to using ES cells to combat disease for instance, if it's a disease caused by germ line then there's no way we can use ES cells to resolve the germline disease. In addition, maintaining balance between cell apoptosis/cell growth.

The beauty of science is that there's no absolute answer right? :D So there's always room for imagination!

As for why Nature created us and subject us to programmed death; perhaps we can only get the answer from Mother Nature. Just like till now, we still can't answer the question on egg-first-or-chicken-first.


-I don't want to be immortal; living can be quite tiring-
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Postby Moocow4u2 » Sun Mar 28, 2010 3:19 am

I don't think it's possible, if it was we'd over populate the world so we would need more space for housing and stuff like that and eventually we would run out of space or have food shortages trying to feed everyone alive. so I think if immortality was possible and nobody was dying people would eventually be starving to death and we would have lots of people living on the streets.
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Postby kolean » Mon Mar 29, 2010 3:00 am

Do you think that if we had the chance for immortality (anybody), that the way society thinks and acts would not be changed? Like for example, procreation. Why would you want to procreate? And sure, the pleasure of sex will still be there, but wouldn't you be more selective? as you could possibly have the chance to have everyone at one time or another (LOL!). I think it would change the way society conducts itself.
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Postby JackBean » Mon Mar 29, 2010 8:09 am

do you think, that people would not want kids anymore? The question is, whether the immortal people would be forever young or some old people who are damn still here! :)
In the first case, the wish for kids could be reduced (or at least you could have them when e.g. 100 years old:), but IMHO people would still like to have some kids...

Cis or trans? That's what matters.
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