Join for Free!
121440 members

pancreatic β-cell calculation

Discussion of all aspects of cellular structure, physiology and communication.

Moderator: BioTeam

pancreatic β-cell calculation

Postby sweety_girl » Wed Nov 29, 2006 12:59 pm

I don't know how to answer this question.. can anyone help?

A pancreatic β-cell that is cuboidal in shape (10 μm unit length) produces 1 million molecules of
insulin (molecular weight = 5600 daltons) that are stored in dense core secretory granules, each
approximately 300 nm in diameter. Calculate the following:

I) If the insulin-containing granules occupy 10% of the cell volume, how many granules are present
in each cell ?

II) After an extensive chocolate binge, if a quarter of the insulin-containing vesicles fuse with the
plasma membrane releasing their contents, what is the percentage change in surface area for a cell?

III) What is the molar concentration of insulin in each secretory granule?
Posts: 5
Joined: Mon Oct 09, 2006 4:56 pm

Postby canalon » Wed Nov 29, 2006 1:40 pm

1) volume of cell*10% divided by volume of a granule
2)(Number of vesicle*surface of vesicle*25%)*100/surface of the cell
3) volume of a granule/number of moles of insulin

USing your brain help even in biology.

Science has proof without any certainty. Creationists have certainty without
any proof. (Ashley Montague)
User avatar
Inland Taipan
Inland Taipan
Posts: 3909
Joined: Thu Feb 03, 2005 2:46 pm
Location: Canada

Return to Cell Biology

Who is online

Users browsing this forum: No registered users and 1 guest