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Wound Healing

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Wound Healing

Postby Squawkbox » Thu Oct 19, 2006 12:25 pm

does anyone know where i could find a flow diagram of wound healing phases or something which lists the order things happen, ive tried google but theres nothing very clear which mentions specific cells etc.

tvm squawkbox :shock:
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Postby Dr.Stein » Thu Oct 19, 2006 2:02 pm

Is this what you are looking for?

Cascade Reaction of Blood Clotting

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Postby honee_v » Thu Oct 19, 2006 2:32 pm

u always have nice pix doc :D

thats about the start of the healing process.. wen the extent (e.g. depth, loss of tissues) of the wound is considered the process could vary... a cut may heal by mere wound closure, but if chronic like an ulcer, or burn injury, by contraction and reepithelialization...


^_^
Last edited by honee_v on Thu Oct 19, 2006 3:21 pm, edited 2 times in total.
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healing process in general 3 phases

Postby honee_v » Thu Oct 19, 2006 3:06 pm

most wounds would undergo 3 general phases: inflammatory, proliferative and tissue remodelling phases

starts with blood clotting --> sends out signals to call for polymorphonuclear cells... then comes the monocytes (for phagocytosis and release of growth factors)... these generally happen during inflammatory phase...

then the proliferative phase, which consists of about 3 processes: fibroblast proliferation (for collagen deposition and wound contraction) and epithelial proliferation (to generate new epithelial cells) and angiogenesis - basically to replace damaged or lost cells

lastly the tissue remodelling phase, which is remodelling (collagen degradation, resynthesis and maturation) and scar formation... all these are in general... healing process involves several mechanisms...


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links for wound healing

Postby honee_v » Thu Oct 19, 2006 3:16 pm

if you like you can also view this:

http://www.residentnet.com/bsframe.htm

at the bottom u can choose levels: 'in brief' or 'in depth'

hope this also helps



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Postby Dr.Stein » Thu Oct 19, 2006 3:23 pm

As you see, I am not sure which one Squawkbox wants. Thus I provided the beginning of the process. You can see my question mark up there ^ ;)
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Postby honee_v » Thu Oct 19, 2006 3:27 pm

u always got nice pix to share... seems u also teach doc ei?

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Postby sdekivit » Thu Oct 19, 2006 9:01 pm

the book 'Pathologic Basis of Disease' by Cotran et al describes in 2 chapter the acute, chronic inflammation and the following angiogenesis en tissue healing and remodelling.
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Postby Dr.Stein » Fri Oct 20, 2006 2:47 am

honee_v wrote:u always got nice pix to share... seems u also teach doc ei?

^_^

Yes, I am a teacher. I should provide nice pics and slides to make my students happy in the class ;)
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Postby sdekivit » Fri Oct 20, 2006 8:38 pm

or impress them with complicated signal transduction cascades :twisted:
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Postby honee_v » Sat Oct 21, 2006 1:19 pm

sdekivit wrote:or impress them with complicated signal transduction cascades :twisted:



so not :)

sumtimes visuals are better than plain talk.. esp in science... & sumtimes visuals speak more


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Postby Dr.Stein » Sun Oct 22, 2006 2:32 am

sdekivit wrote:or impress them with complicated signal transduction cascades :twisted:

You mean ITIM/ITAM? Whoa I love that! :) Also apoptosis mechanism with Fas ligand but not my students :roll: :lol: They think they are full enough with Complement Pathways 8) I have no idea why, but Complement Pathways are "funny". I have a nice animation for it, unfortunately it came late after the class was over :( So nect semester! :twisted:
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