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centrosomes

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centrosomes

Postby sweety_girl » Mon Oct 09, 2006 4:58 pm

hey people..

I was just wondering how exactly does a centrosome know when it has found the center of a cell. Can anyone explain this to me. thanx in advance
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Postby MrMistery » Mon Oct 09, 2006 6:32 pm

well it doesn't cause the centrosome is not in the center of the cell. the centrosome is located laterally from the nucleus. it is never at the edge of the cell however, perhaps because the microtubules that extend from it keep it from moving to the extreme sides of the cell...
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Postby druid » Fri Oct 20, 2006 6:39 am

Center-seeking behavior of centrosome:
http://www.ncbi.nlm.nih.gov/entrez/quer ... iggrp.3001

A microtubule array can find the center of a cell:
http://www.ncbi.nlm.nih.gov/books/bv.fc ... iggrp.3002
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Postby MrMistery » Fri Oct 20, 2006 5:28 pm

Hey i was right :D
But i still say that in a cell the centrosome is not in the center of the cell. Cause the nucleus is there, right?(guess it depends on the kind of cell too..)
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Postby druid » Fri Oct 20, 2006 7:17 pm

MrMistery wrote:Hey i was right :D
But i still say that in a cell the centrosome is not in the center of the cell. Cause the nucleus is there, right?(guess it depends on the kind of cell too..)


No, not right. Centrosome can find the center of a denucleated plasma:
http://www.ncbi.nlm.nih.gov/books/bv.fc ... iggrp.3002
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Postby MrMistery » Sat Oct 21, 2006 7:53 am

i meant i was right about how the centrosome does not drift to the edge of the cell. Yeah, sure if the cell has no nucleus it would wind up in the center according to the law of physics, but for the center of the cell, it's first come, first serve.
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Postby Dr.Stein » Sun Oct 22, 2006 2:21 am

According to its name, it refers to the center:

Centrosoma = central (adj. centre) + soma (body)

or

Centriola = central (adj. centre) + -iol (something small)

But I believe it does not exactly locate in the centre because nothing is perfect :)
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