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about the theory of biology

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about the theory of biology

Postby victor » Sat Apr 30, 2005 1:08 pm

Theorycaly, biology allows us to transfer our blood to the recepients with these criterias. First, the recepients must have the same blood type as ours. Second, if the blood type between us and the recepients aren't the same type, theorycally we can trasfer it if they have the same aglutinogene and the anti-aglutinogene. But, when I read biology book, I found that AB blood type is the universal recepients. This statement makes me confuse, because when AB type is receiving blood from A type theorycally (because AB is universal recepients), it is said that theorycally nothing will happened after the transfusion. A type have Alpha-aglutinogene and Anti-beta-aglutinogene meanwhile AB have both of Alpha-aglutinogene and beta-aglutinogene without containing any Anti-alpha or anti-beta. What I wanna ask is how come we can theorycally say that A type which has Anti-beta can make the transfusion succesfully to the AB type which has Beta-aglutinogene?? As we know that if an aglutinogene meets it's anti, they will be koagulated and we can see from those two statements above which is written that A has an Anti-beta meanwhile AB has an Beta-aglutinogene.....
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Postby MrMistery » Sun May 01, 2005 12:42 am

The aglutionogenes on the surface of the red blood cells of the person with AB are bind together. Thus it would require both anti-alpha and antu-beta antibodies to lead to lysis.
In my opinion, this is the easiest way you can understand this situation. This is a very complex cellular biology question. Those aglutiongenes are themselves a sort of glicoproteins(actually they are called proteoglicans in this case) but you needn't know all this...
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