Discussion of all aspects of cellular structure, physiology and communication.
OK. Let me start off by saying that this is my first post here, I just joined about 2 seconds ago.
Also, please go easy on me, as I'm only 15, and I've only completed grade 9 Science. This is probably an idiotic idea and there's a reason why it wouldn't work, but I'd like to know:
Would it be possible, in any way, to fertilize an egg with the nucleus of another egg? Somewhat like cloning, except, instead of replacing the entire nucleus, adding the nucleus of another egg.
I understand (or at least I hope I understand) how reproduction all works- how you have to have two haploid cells to combine to form a diploid cell, so it can undgergo mitosis and all that rot.
So yes, I know this is probably way off. Oh yes, and I assume, that if this were possible, it would only produce females. Correct?
Thank you for any input.
Last edited by EmilyElle on Thu Apr 28, 2005 12:24 am, edited 1 time in total.
If I understand you correctly, you're talking about using an egg cell as a sperm cell?
Ummm that would be very interesting to see, but I think it could work(something like invitro).
Well yes if it works it would only produce females.
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Ahaha, yes, it would be VERY interesting- not to mention complicated, seeing as you'd also have to provide initial energy for the cell to develop before it attaches to the placenta... along with the usual fiddly complications of IVF.
I was just wondering if it'd work.
Yeah. interesting idea. And i believe its already under development. Its been done with embryos from mice. Have a look at the link:
http://www.telegraph.co.uk/news/main.jh ... fert10.xml
And thats news from 2001.
Edit: Just realised that you were talking about nucleus from another egg and not nucleus from any cell in the body. So i didnt really answer the right question. If you could put mitochondria in the egg then the energy issue wouldnt be a problem.
Mice experiment :I read in Genome by Matt Ridley(XV chapter) that in the case of 2 mothers(eggs) the embrio couldn't form the placenta and in case of 2 fathers(spermatozoids) the Very big placenta was formed but the embryo was just group of disordered cells .I don't know the reason.You people?
Sorry on my English.
I'm guessing that the genes for forming the placenta are located on the Y cromozome. If it were in a homozygotus state it would determine an overdeveloped characteristic(in our case, the placenta)
"As a biologist, I firmly believe that when you're dead, you're dead. Except for what you live behind in history. That's the only afterlife" - J. Craig Venter
Probably not a good guess, since XX cells lead to normal zygotes and a normal placenta, don't you think?
That is usually where epigenetics is called into action. An other way to say that noone really has an idea At least, I don't.
You are right PAtrick... where the heck was i thinking?
I'm in the dark at this one... Anyone got an idea?
It has to do with sex-specific DNA methylation and organization. Sperm DNA and Oocyte DNA are both DNA, but not organized, structured, and methylated the same. Some structures/processes the sperm DNA is expected to manage and some the oocyte DNA is expected to manage.
*edited for spelling*
WOW ! Thanks!!!
Aah... Jelanen knows everything....
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