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Multiple proteins encoded in single operon

Discussion of all aspects of biological molecules, biochemical processes and laboratory procedures in the field.

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Multiple proteins encoded in single operon

Postby neon » Fri Jun 09, 2006 9:07 am

Hi there,

I have a trivial question on prokaryotic operons:

I understand the separate regions of an operon, but how can multiple proteins be encoded within a single operon. Essentially, I dont understand how "the system" would know where one protein stopped and another began. I gather there is the stop codon, but I thought this would signify the end of transcription rather than the ending of a polypeptide and the start of another.

If I am wrong, and it is the stop codon that signifies the end of one protein coding region and another, then what is responsible for the termination of the transcription process - i.e. how would the holoenzyme know when to stop transcribing the DNA?

Thanks very much in advance!

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Postby oppox » Fri Jun 09, 2006 10:43 am

I may be wrong but isnt it the stop codon that terminates the protein synthesis and a special terminator region that stops the transcription, like the T7 terminator region.
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