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Calcium regulated muscle cell contractionModerator: BioTeam
2 posts • Page 1 of 1
Calcium regulated muscle cell contractionI know that when a muscle cell receives a signal to contract, the sarcoplasmic reticulum releases Ca++ (which then binds to tropomyosin allowing myosin head to walk up the actin filament) but I have been told that a Ca++ deficit will cause the muscle cell to contract and not be able to release. What piece of information am I missing to make these facts coherent?
Follow up question: is this at all related to rigor mortis?
the muscle fiber will relax when no Ca(2+) is available.
It's true, though, that a deficit in ATP will cause muscle stiffness because in the ADP-form the myosinheads cant release from the troponin, which is Ca(2+) dependant in making a bindingsite for myosin. (in rigor mortis Ca(2+) will diffuse out of the ER but no ATP is available leading to stiffness of the corpse)
2 posts • Page 1 of 1
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