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who's your favourite biologist?

Debate and discussion of any biological questions not pertaining to a particular topic.

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Postby 2810712 » Fri Apr 14, 2006 6:23 am

My favourite is Malvin Calvin, Rosalind Franklin &
Myself as a 'micro'BIOLOGIST' :wink:

I like CytchromeP as well...






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Postby angel » Sat Apr 15, 2006 4:29 am

Jelanen wrote:Kary Mullis is the researcher who found heat resistant polymerase for use in PCR.


no, Karry Mullis used E.Coli polymerase for his PCR experiments. It was Saiki later in 1988 who used thermostable poymerases here and made PCR a revolution
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Re: who's your favourite biologist?

Postby angel » Sat Apr 15, 2006 4:31 am

kabuto wrote:just for fun.......
:shock: :shock: :shock: :shock:

Rosalind Franklin: hope she would have got the credit for the decephering the double helix of DNA
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Postby Jelanen » Sat Apr 15, 2006 11:56 am

no, Karry Mullis used E.Coli polymerase for his PCR experiments. It was Saiki later in 1988 who used thermostable poymerases here and made PCR a revolution


Ok, you might get a softer landing from other people on this one, but this is one of my pet peeves. Not so much that you corrected me(happened before, will happen again), but that you didn't provide any proof as to the validity of your statement. Since this is a website dedicated to science, wouldn't it be prudent to provide some links or book references to back up your contradiction of my statement? Don't worry, I'll do the work..this time.

http://en.wikipedia.org/wiki/Thermus_aquaticus
Pay particular attention to the Idea Number Two: Thermostable Taq Polymerase heading near the bottom of the page

Now, I did google searches in multiple parameters and Saiki is listed as the primary author on the seminal 1988 article Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase., K. Mullis is also listed as an author. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=2448875

Seems there is some controversy in this area, but since the reference to Mullis as a the discoverer is on wikipedia and the pubmed article lists Saiki as the primary author, I would lean more towards Saiki. Now, the article that I read when I was doing my (cursory) initial look listed Mullis as the discoverer, hence why I listed it.

Now, the point of my little rant here isn't to start a fight over the Taq issue, but to point out that this is a website dedicated to biology, not slashdot or some other mass market forum. We're supposed to be biologists of some form or another, whether students, professionals, or profs and I think its fair to expect a higher level of discussion than simple contridictory statement.

That is all...for now.
-Jelanen 8)
'It is futile to pretend to the public that we understand how an amoeba evolved into a man, when we cannot tell our students how a human egg produces a skin cell or a brain cell!'

Dr Jérôme J. Lejeune
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Postby Enzyme » Sun Apr 16, 2006 2:58 pm

Jelanen, I'm glad to see your last post (I liked it). It shows the personality of a true Biologist, he he. All the people who want to dedicate their lives to Science have to be nonconformists. This is one of the basis of research.

You shouldn't base a fact on one simple statement. You have to get a lot of good information (and read it, of course), to research, to pry, to link causes and to make hypothetical cases.

Nice post ;). See you!
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Postby angel » Mon Apr 17, 2006 6:45 am

Jelanen wrote:
no, Karry Mullis used E.Coli polymerase for his PCR experiments. It was Saiki later in 1988 who used thermostable poymerases here and made PCR a revolution


Ok, you might get a softer landing from other people on this one, but this is one of my pet peeves. Not so much that you corrected me(happened before, will happen again), but that you didn't provide any proof as to the validity of your statement. Since this is a website dedicated to science, wouldn't it be prudent to provide some links or book references to back up your contradiction of my statement? Don't worry, I'll do the work..this time.

http://en.wikipedia.org/wiki/Thermus_aquaticus
Pay particular attention to the Idea Number Two: Thermostable Taq Polymerase heading near the bottom of the page

Now, I did google searches in multiple parameters and Saiki is listed as the primary author on the seminal 1988 article Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase., K. Mullis is also listed as an author. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=2448875

Seems there is some controversy in this area, but since the reference to Mullis as a the discoverer is on wikipedia and the pubmed article lists Saiki as the primary author, I would lean more towards Saiki. Now, the article that I read when I was doing my (cursory) initial look listed Mullis as the discoverer, hence why I listed it.

Now, the point of my little rant here isn't to start a fight over the Taq issue, but to point out that this is a website dedicated to biology, not slashdot or some other mass market forum. We're supposed to be biologists of some form or another, whether students, professionals, or profs and I think its fair to expect a higher level of discussion than simple contridictory statement.

That is all...for now.
-Jelanen 8)


Sorry Sir,
If you felt offended with my statement. I was just making my point what I have read about the discovery. I mostly refer Sambrook et al for molecular biology topics and I got the point from it. And I agree science topics are not for fight but for discussion. And I am very inexperienced as you all must be in this field , so if you disliked something then I am sorry.
As for Karry Mullis, he is indeed credited as the discoverer, but my point is can we neglect the ideas og H.G. Khorana and the use of thermostable polymerase in PCR, which made it so successful.
I just want to know your views, hope you'll answer
Thank You
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Postby cartener » Fri Apr 21, 2006 10:39 am

I like the molecular scientist Francis crick. who put forward the double helix model of DNA and the central dogma of genetic flow, I like him to nominate his theroy with the word "dogma"
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Postby Zeneth Entorion » Sat Apr 22, 2006 5:00 pm

If we can include fictional biologists I would have to say Kaye Lang from Darwin's Radio by Greg Bear.

Otherwise, I rather like Craig Venter. Possibly just because few other people do. By playing the competition and trying to run an independent, profit-based genome sequencing operation, he helped to speed up the mainstream HGP.
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Favorite Biologist

Postby Doc44 » Mon Apr 24, 2006 1:55 am

ah......me.

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Postby Mjhavok » Tue Apr 25, 2006 1:17 am

Gregor Mendel

The man discovered alot with little scientific background.
Forgive him, for he believes that the customs of his tribe are the laws of nature!
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Postby kabuto » Mon May 01, 2006 3:49 am

Mjhavok wrote:Gregor Mendel

The man discovered alot with little scientific background.


he cheat!! :lol: :lol:
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Postby Mjhavok » Mon May 01, 2006 8:40 am

kabuto wrote:
Mjhavok wrote:Gregor Mendel

The man discovered alot with little scientific background.


he cheat!! :lol: :lol:



Can you explain this? "he cheat"
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