Biology-Online • View topic - 2 Genetics questions
Login

Join for Free!
122511 members
Advertisement
Advertisement

2 Genetics questions

Discussion of all aspects of biological molecules, biochemical processes and laboratory procedures in the field.

Moderator: BioTeam

2 Genetics questions

Postby DeltaHQ » Thu Apr 20, 2017 8:36 pm

1) A child born to a perfectly healthy family was diagnosed with a rare disease. After abnormal behavior in the child, the family decided to get his DNA checked via 23andme company and also consult an oncology doctor. The child was diagnosed with chronic myelogenous leukemia. When the sequence of his DNA was retrieved, the doctors told the parents of the child that the chromosomal sequence of the child was different than his parents. In fact, especially one of the chromosomes (chromosome 8) looked extensively long (like chromosome 1). How could this child acquire this kind of extension in the chromosome?

2)What are the two terminators in prokaryotes and how do they work to stop transcription?
DeltaHQ
Garter
Garter
 
Posts: 1
Joined: Thu Apr 20, 2017 8:33 pm

Re: 2 Genetics questions

Postby Vmedvil » Mon Aug 14, 2017 2:05 pm

Well, he acquired this extra long chromosome due to the fact that another chromosome at one point broke off and stuck to the one with the extra long chromosome it happens sometimes due to failures in DNA repair pathways probably Double-Strand Break Repair.


Secondly, Terminators, the two types are (1) rho-independent terminators and (2) rho-dependent terminators. Basically, both types stop the RNA Polymerase from continuing to transform the DNA into RNA at those points which terminates the Transcription. There is a RNA chain that blocks attached to a hairpin the RNA polymerase's active site in rho-independent terminators and in rho-dependent terminators there is a amino acid chain with rho on it that blocks the RNA polymerase's active site.
Einstein would turn over in his grave. Not only does God play dice, the dice are loaded.
-26 Dimensional Quadratic Super String Theory
User avatar
Vmedvil
Garter
Garter
 
Posts: 23
Joined: Mon Aug 14, 2017 11:59 am


Return to Molecular Biology

Who is online

Users browsing this forum: No registered users and 1 guest