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transgenic animals

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transgenic animals

Postby sandy » Fri Jan 13, 2006 6:35 am

how do animals become transgenic?
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Postby Dr.Stein » Fri Jan 13, 2006 8:34 am

It is when their body contain genes transfered from another organism(s) :)

Look at here 8)

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Legend:

Illustration of how transgenic mice are produced.

Genes responsible for particular traits or disease susceptibility are chosen and extracted. Next they are injected into fertilized mouse eggs. Embryos are implanted in the uterus of a surrogate mother. The selected genes will be expressed by some of the offspring.

Since the first gene transfers into mice were successfully executed in 1980, transgenic mice have allowed researchers to observe experimentally what happens to an entire organism during the progression of a disease. Transgenic mice have become models for studying human diseases and their treatments.
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Postby appleguo » Mon Jan 23, 2006 2:56 pm

Does it also mean that even if the animal is transgenic, it does not necessarily produces offspring with the desired genes?
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Postby Dr.Stein » Tue Jan 24, 2006 7:45 am

Naturally, we cannot choose which genes we desire in our offspring...
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Postby aileen » Fri Jan 27, 2006 9:26 am

that is they contain genes which are really alien into there system.. a particular gene of desired characteristics is injected.. (try reading melcular biology books, or use google)
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Postby baikuza » Fri Jan 27, 2006 12:32 pm

hey.. you said mouse egg? i do not think so. it is vivipar, not ovipar
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Postby Dr.Stein » Sat Jan 28, 2006 6:04 am

baikuza wrote:hey.. you said mouse egg? i do not think so. it is vivipar, not ovipar

VERY FUNNY! :lol: egg = ovum tsk...tsk...tsk :evil:
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Postby baikuza » Mon Jan 30, 2006 1:26 am

ovum differ with egg. egg has strong shale, but ovum not. ovum always haploid(normally).egg can be diploid or haploid.
by the way... please do not use any confusious figure for explain some thing. that makes some one is thinking the wrong....(look at your fig. above.)
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Postby Dr.Stein » Mon Jan 30, 2006 9:19 am

Excuse me, how long have you been in Biology? I do not mean to offend you but the term "egg" is common to refer to "ovum". I do not mean to be arrogant, but I have been in Embryology and Reproductive Biology and using egg or ovum doesn't mater for us in those fields.

Reptilian (oviparous) and birds egg, oviparous mammal eggs, and also most terrestrial invertebrates eggs are protected by hard shell because they will laid in external and dry environment, means that they need extra protection to become survive. Toads eggs are protected only by slime because they are kept in the water. Frogs eggs are protected by foamy structure because they are laid out of water but they need a moisture for embrios to able to survive. They are just some examples. Now you can compare with viviparous reptiles and mammals. I hope this is clear for you now.

Any questions, arguments, and other things are always welcome ;)

P.S. I cannot see other users are confused :P If you are confused then ignore it, and try to find another figure for yourselves, that's quite easy :lol:
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Postby baikuza » Wed Feb 01, 2006 9:52 am

okay...

i can accept this.

(^ ^)
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