HERE'S A SNIPPET FROM AN EASY TO READ ARTICLE RE: ARSENIC
WHAT I THINK WE ALL HAVE BEEN EXPOSED TO FROM THE PESTIDCIDES!!! I WILL PUT THE HYPERLINK IN CASE YOU WANT REST OF THE ARTICLE.
iT TALKS ABOUT GLUCOCORTICOID-RECEPTOR COMPLEX TOO
"Thus, if environmentally relevant doses of arsenic are
able to suppress the normal function of GR as a mediator of gene regulation, as suggested by our results, we hypothesize that this may contribute to its ability to promote tumorigenesis and contribute to other pathophysiological states in these tissues. This unique mechanism would suggest further that arsenic
may be able to act synergistically with other toxic and carcinogenic agents to increase disease risk, which is supported by epidemiological data that indicate a synergistic increase from cigarette smoking and exposure to arsenic. Because arsenic contamination of drinking water is widespread in the United States and elsewhere, and it is usually found in combination with many other toxic chemicals at most Superfund and other toxic waste sites, these combined exposures may represent a significant human health risk. "