Login

Join for Free!
66249 members
Home Forum Dictionary Articles Tutorials Books Directory Share your work


drugs and heart rate

Discussion of all aspects of cellular structure, physiology and communication.

Moderator: BioTeam

Post a reply

drugs and heart rate

Postby countyclare » Mon Dec 12, 2005 5:06 am

Does anyone know of a good journal article that talks about the mechanisms and subsequent effects of ethanol and caffeine (separately) on heart rate? I know ethanol decreases heart rate and caffeine increases, but how is what I am unsure of. Thanks in advance to anyone who can help me!!! :o
User avatar
countyclare
Garter
Garter
 
Posts: 2
Joined: Mon Dec 12, 2005 5:04 am
Top

Postby chicoguardian » Mon Dec 12, 2005 12:56 pm

try this site, I think think it should have plentful enough info that you will need... http://kidshealth.org/teen/drug_alcohol ... drugs.html
Life is not of comedy but tragedy, life lives and then dies in sorrow
User avatar
chicoguardian
Coral
Coral
 
Posts: 121
Joined: Wed Oct 19, 2005 12:18 pm
Top

Postby MrMistery » Mon Dec 12, 2005 6:53 pm

Don't knwo about alcohol's effect on heart cells, but i do know that caffeine activated something called the Rynoadin receptor, a protein located in the endoplasmic reticulum. This is actually a calcium channel that transports it via facilitated diffusion into the cytoplasm. Another level where caffeine function is that it inhibits the production of an enzyme named phosphodiesterase that results in cAMP not being recycled.
About alcohol, all i know about influences on the cardiovascular system is that it determines a peripherical vasodilatation
"As a biologist, I firmly believe that when you're dead, you're dead. Except for what you live behind in history. That's the only afterlife" - J. Craig Venter
User avatar
MrMistery
Inland Taipan
Inland Taipan
 
Posts: 6832
Joined: Thu Mar 03, 2005 10:18 pm
Location: Romania(small and unimportant country)
Top

Postby countyclare » Mon Dec 12, 2005 11:50 pm

Thanks! :)
User avatar
countyclare
Garter
Garter
 
Posts: 2
Joined: Mon Dec 12, 2005 5:04 am
Top

Postby sdekivit » Tue Dec 13, 2005 8:21 pm

MrMistery wrote:Don't knwo about alcohol's effect on heart cells, but i do know that caffeine activated something called the Rynoadin receptor, a protein located in the endoplasmic reticulum. This is actually a calcium channel that transports it via facilitated diffusion into the cytoplasm. Another level where caffeine function is that it inhibits the production of an enzyme named phosphodiesterase that results in cAMP not being recycled.
About alcohol, all i know about influences on the cardiovascular system is that it determines a peripherical vasodilatation


those receptors are called ryanodine receptors and are involved in the so called calcium-induced calcium-release.

cAMP is also very important in the cardiac contraction, since cAMP binds to the If-channels in the sinoatrial node holding them open for a longer period and thus an increased heart rate.
sdekivit
King Cobra
King Cobra
 
Posts: 586
Joined: Sat Jul 30, 2005 7:16 pm
Location: holland
Top

Postby MrMistery » Wed Dec 14, 2005 8:04 pm

spelling is my problem, as always. Oh yeah i forgot to write why cAMP is important. Luckly sdekivit is on guard.
"As a biologist, I firmly believe that when you're dead, you're dead. Except for what you live behind in history. That's the only afterlife" - J. Craig Venter
User avatar
MrMistery
Inland Taipan
Inland Taipan
 
Posts: 6832
Joined: Thu Mar 03, 2005 10:18 pm
Location: Romania(small and unimportant country)
Top
Post a reply

Return to Cell Biology

Who is online

Users browsing this forum: No registered users and 1 guest