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Too many ions inside a neuron cell. What happens?

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Too many ions inside a neuron cell. What happens?

Postby Coelacanth » Tue Dec 03, 2013 1:34 am

For example, there are diseases where the sodium channel cannot gauge voltage difference effectively, and so it remains open, rapidly building up a concentration of sodium ions in the cell, and this disorder often affects potassium channels, so there is practically no way that the excess sodium ions can escape as they rush into the neuron. What happens when (too many) sodium ions rush into a neuron cell, with no way of them escaping (defective or inactivated K channels)?

What happens? Assuming there's a constant, rapid influx of sodium ions with no means of escape. What happens to the voltage and the cell?
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Postby JackBean » Tue Feb 25, 2014 9:20 am

Since it's passive transport, the concentration will never be higher than in extracellular space.

Cis or trans? That's what matters.
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