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Wobble theory and transposons

Genetics as it applies to evolution, molecular biology, and medical aspects.

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Wobble theory and transposons

Postby bilalzq » Fri Nov 04, 2005 3:39 pm

hey guys! i need urgent fast reeplies! i have 2 questions!
Q1: According to the wobble rules, the correct amino acid can be added to a growing polypeptide chain even if the third base in an mRNA codon does not correctly match the corresponding base in a tRNA anticodon. How do the wobble rules and the redundancy of the genetic code relate
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Q2Describe the difference between a simple and composite transposon in bacteria.
Which could help bacteria adapt to new environments? Explain how.
.................
please help me out
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Postby thecow135 » Sat Nov 05, 2005 10:53 pm

Q1: According to the wobble rules, the correct amino acid can be added to a growing polypeptide chain even if the third base in an mRNA codon does not correctly match the corresponding base in a tRNA anticodon. How do the wobble rules and the redundancy of the genetic code relate

this is because the base doesnt need tto amtch the corresponding base because it is not reaaly needed. this proves that that code is already sumwhere else, thus the redundancy
CUZ EVERYBODY NOE THAT THE GAME DONT STOP TRY TO MAKE IT TO THE TOP
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Postby siya » Sun Nov 06, 2005 5:43 am

Q1--only first two base are sufficient to code for the the required amino acid,the third base is present so that the mRNA can get properly attached to the tRNA.hence even though the third base does not match due to mutation or otherwise the correct amino acid can still be added to the growing polypeptide chain.got it.
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Postby Dr.Stein » Sun Nov 06, 2005 11:10 am

THISis about bacterial transposon, maybe it could help you a bit... ;)
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wobble hypothesis and transposons

Postby lara » Wed Nov 09, 2005 11:24 am

wobble hypothesis is not just random base pairin at the third site.if so, how do u think the machinery knows which aminoacid to select?for instance,serine &arginine?(they differ only by the third base)
uracil can only wobble with A and G.there are such restrictions for the wobbling of other bases.check it out,they wobble in such a way that the amino acid doesn't change!!!
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wobble hypothesis

Postby phage » Fri Nov 11, 2005 8:00 am

that was so nice,lara!!
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