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Pedigree Analysis

Genetics as it applies to evolution, molecular biology, and medical aspects.

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Pedigree Analysis

Postby chapsticks4 » Tue Feb 26, 2013 7:06 pm

I want to know if I have this correct because I am confused.
I think this is x-linked recessive is that right :?:
since it can fall into this category
1.Usually more males than females are affected.
2. Affected sons are usually born to unaffected mothers;
thus, the trait skips generations.
3. Approximately half of a carrier (heterozygous) mother’s
sons are affected.
4. Never passed from father to son.
5. All daughters of affected fathers are carriers.

Also I am unsure if the genotypes are correct
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chapsticks4
Garter
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Postby Cat » Sun Apr 28, 2013 3:09 pm

1. Cannot be x-linked recessive: in order to have an affected female progeny, you need to have heterozygous carrier mother AND father. That means that father would be affected too (single X chromosome).
2. Thus, it's an autosomal (see above) recessive (since neither parent affected, it cannot be dominant).

Tip: in pedigree analysis you must identify what it cannot possibly be and then you will be left with only possibility.
Cat
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