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λ Phase Genetic Switch

About microscopic forms of life, including Bacteria, Archea, protozoans, algae and fungi. Topics relating to viruses, viroids and prions also belong here.

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λ Phase Genetic Switch

Postby Helics » Sun Oct 28, 2012 8:22 am

λ phase infect K-12 starin of E.coli, it insert it's DNA inside the E.coli cell. How the phase DNA discriminate the host genomes from plasmid DNA ? can you please help me ?
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Postby lenni » Thu Nov 01, 2012 10:08 am

the λ-phage inserts his DNA by recombination; the integration is site-specific, the recognition-site is found to by 15bp long and is located between the gacactose and tryptophan genes...
My thesis: as long as the plasmid DNA doesn`t contain the recognition-sequence, the integration of the λ-DNA is restricted to the bacterial chromosome
but I am not sure; maybe it is caused by another mechanism...
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