Gluconeogenesis

by **billyfisher100** » Tue Jun 19, 2012 2:40 pm

Hello all.

What is the origin of HCO3- where it enters at the first step of gluconeogenesis? Is it from carbonic anhydrase?

Thanks :)

by **JackBean** » Tue Jun 19, 2012 5:07 pm

There is equilibrium between CO2 and (HCO3)-

by **JackBean** » Tue Jun 19, 2012 5:09 pm

And yes, the equilibrium is maintained by carbonic anhydrase, but even without it there would be some (HCO3)-, but it could be replenished quickly.

by **billyfisher100** » Thu Jun 21, 2012 5:30 pm

Thanks very much! Is there any compartmentalisation of carbonic anhydrase, or can it be present anywhere?

by **JackBean** » Thu Jun 21, 2012 5:58 pm

http://www.brenda-enzymes.info/php/resu ... no=4.2.1.1
look for localization (seems to be present basically everywhere)

by **billyfisher100** » Mon Jul 02, 2012 5:27 pm

Thanks