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Genetics as it applies to evolution, molecular biology, and medical aspects.

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Postby futurebrewer » Tue May 22, 2012 8:40 am

Hello all. I am having a really hard time with this problem. If you could walk me through this that would be great. Thanks! Here are the questions:

If p and q are frequencies of alleles, what is q if p=0.85?

ok, I know the answer is .15, that was easy!

Next question: In a population of 50 individuals, how many q alleles are present? I know the answer is 15, but I do not know how to get that answer.

Now this next part, I have NO clue how to solve:

You sampled 100 individuals from a population of douglas fir trees to find susceptibility to root rot disease. You genotyped your sample and found 53 trees were homozygous for one allele (p) and 19 were homozygous for another allele (q) on the same gene

a.) What is the estimated genotype frequency of the population?

pp? pq? qq?

b.) What is the estimated allele frequency of the population?

p? q?

c.) What is the expected genotype frequency at Hardy-Weinberg equilibrium?

pp? pq? qq?
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Postby JackBean » Tue May 22, 2012 8:50 am

How many alleles there are in total in population of 50 individuals (probably eukaryotic organisms)

a) pp is obviously 53 of 100 and qq is 19 of 100. How many is left for pq?

b) p = sqrt(p^2) and q = sqrt(q^2)

c) here you should probably take the frequencies calculated in b and put into HW equation.

Cis or trans? That's what matters.
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