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Gene enhancers/repressors in Drosophilia stripes

Discussion of all aspects of biological molecules, biochemical processes and laboratory procedures in the field.

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Gene enhancers/repressors in Drosophilia stripes

Postby bwooten28 » Wed Apr 04, 2012 4:44 am

Hey guys,

Question that I can't seem to answer correctly/articulate in the right way.

Gene expresses 2 stripes, 1 in the anterior and 1 in the posterior. The same activator binds to both enhancers and is required for expression in both the ant and post stripe. Activator is present in an ant/post gradient.
Describe a mechanism by which the enhancers might specify the 2 stripes. You may use the activity of a repressor. You may modulate the affinity or number of binding sites (but not both) in Enhancer A and B.
*In the mechanism, what would be the effect on expression pattern if you deleted enhancer A?
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Postby bwooten28 » Wed Apr 04, 2012 4:56 am

I know it has to deal with having repressors interacting with the enhancers at different gradients along the fly and when enhancers are "on", transcription can occur and a stripe can be made. I just can't seem to understand the details behind this.
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