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genetic diseases of dogs

Genetics as it applies to evolution, molecular biology, and medical aspects.

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genetic diseases of dogs

Postby pokernina » Wed Feb 22, 2012 7:39 pm

If we are going to make working type dogs as household pets(and pets only) while holding on to its working shape, and practice it generations after generations, will that certain type of working dogs get genetic diseases?
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Postby Squirrell » Wed Feb 22, 2012 10:09 pm

Not if there aren't any genetic diseases in the original sire and dam, and no studs or bitches carrying a genetic disease are used for breeding. Inbreeding and poor artificial selection can cause deformities, but not genetic disease.
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Postby JackBean » Wed Feb 22, 2012 11:01 pm

Really? There are no mutations whatsoever?
http://www.biolib.cz/en/main/

Cis or trans? That's what matters.
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Re:

Postby Squirrell » Thu Feb 23, 2012 12:00 am

JackBean wrote:Really? There are no mutations whatsoever?


Not if you start with good working dogs, and use reputable, healthy studs with a clear background, no. Dog breeding is very well monitored and records are kept of all litters and where they've gone, if they've had medical problems, genetic problems, hip dysplasia etc, so it can all be traced back and dogs can be identified as having 'bad genes.'

If you start off with a mating pair with a great genetic history free of genetic diseases (this is usually the case for working dogs), there is no reason that genetic abnormalities would present in future generations unless poor studs are used, breeds are accidentally mixed (like Alsation and German Shepherd*) or the quality of the mates are poor.

*Contrary to popular belief, the German Shepherd and the Alsation are separate breeds. After WWII, Britain engineered the Alsation to have a very slightly different spine. This qualified it as a separate breed, so they could drop the 'German.' Alsations tend to have a shorter life though, as their back is less able to support the weight of their abdomen when geriatric.

Problems can also arise if a bitch is mated too many times (her second litter will usually be the best quality), too frequently, without being vaccinated or whilst sick. These can be avoided by consulting your vet and obiding by the Breeding and Sale of Dogs (Welfare) Act 1999. Please become familiar with this act as well as the Animal Welfare Act 2006 if you wish to breed dogs.

I've been studying a BTEC Extended Diploma in Animal Management for the last two years which, as well as biology, covers animal care, veterinary business, veterinary care and treatment, animal nursing, animal welfare, animal related law and the management of animals in a zoo. Dog breeding has come up quite frequently and we've studied it to some depth.

Regards,
Squirrell
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Re: genetic diseases of dogs

Postby pokernina » Thu Feb 23, 2012 3:06 pm

excerpt from the book "dogs" by biologist raymond coppinger

"There is an even more severe problem occurring in the genetics of the household dog. The working dog was selected to behave in a certain way. The sled dog, for example, was selected to run fast in harness with other dogs. In being selected for that behavior, the dogs evolved a unique shape. This shape allows the dog to behave fast, with stamina. The relationship between shape and behavior is omnipresent.

Therefore, if we want to change the behavior of a dog -- make it more peaceful and less vital -- we must also change its shape. Herein lies the dilemma for the breeder. The audience wants household dogs that are a historical representation of the working-breed shapes, and at the same time they do not want them to display working-breed behaviors. Trying to select for an acceptable household behavior while holding the working shape constant cannot be done. The dog will come apart. It will show genetic diseases. Its hips won't fit together right. The joints will show weaknesses, and the dog will twitch and bleed and each generation will become increasingly miserable."
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Postby RyanRon » Thu Jun 28, 2012 6:51 am

Dog Allergies…
Hello friend, Anybody has any Idea, How Test to my Dog and knows about being Food Allergies or not. And what type of food ingredients is that tend to be problematic for my dog.
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Re:

Postby RyanRon » Thu Jun 28, 2012 12:29 pm

RyanRon wrote:Dog Allergies…
Hello friend, Anybody has any Idea, How Test to my Dog and knows about being Food Allergies or not. And what type of food ingredients is that tend to be problematic for my dog.


I am also looking for pet medicine and vitamins pills to my dog.
Last edited by canalon on Fri Jun 29, 2012 1:03 pm, edited 1 time in total.
Reason: spam removed, author banned
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Postby canalon » Fri Jun 29, 2012 1:04 pm

No need to waste money, your dog is allergic to spam!
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Postby david23 » Sat Jul 21, 2012 6:35 pm

I think you are missing Jackbean's point. Mutations arent always apparent, and only gets unmasked after multiple generations of inbreeding. Even with the good genes, inbreeding and variations you create will lead to defects along the way. Dog breeders, pet makers discard the the defect dogs all the time.

The very idea of creating those purse size pet dogs is itself the accumulation of generations of mutations.

So to the op if you want to breed pet dogs, as in docile, slow, cuddly ones, you better prepare to discard a lot of dogs along the way.
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