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using uniprotModerator: BioTeam
4 posts • Page 1 of 1
using uniprotHello, I am new to bioinformatics and I dont understand what is probably a basic thing about proteins and searching. I dont understand why when I search for something like 'human lysozyme' i wind up with almost 10 different answers, many of which say things like 'lysozyme-like protein'. or lysozyme-g like, or something. what are these different ones, are they all lysozyme? If i was asked to find the sequence of 'human lysozyme', how do i know which one to pick?
Thanks!!
Re: using uniprotalso a similar issue- i have been asked to align human alpha-hemoglobin and human beta-hemoglobin. how do i know if they are talking about the alpha and beta subunits, or there are other entries that just say "alpha-hemoglobin"?
when getting the answers, you should check it one by one
for example:you use the key works " human lysozyme AND organism:"Homo sapiens" " to search on uniprot(http://www.uniprot.org) you will get all 32 results. you can see "Q7Z4W2" is from "Molecular cloning and characterization of three novel lysozyme-like genes, predominantly expressed in the male reproductive system of humans, belonging to the c-type lysozyme/alpha-lactalbumin family"(reference), so it is a true lysozyme also, you can see this result " P61626 " is from " Cloning of human lysozyme gene and expression in the yeast Saccharomyces cerevisiae." (reference) it is what you want to find. maybe in human genome it have many lysozyme gene , the result is not only one
4 posts • Page 1 of 1
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