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Does Langerhan cell in epidermis change to macrophage?

Human Anatomy, Physiology, and Medicine. Anything human!

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Does Langerhan cell in epidermis change to macrophage?

Postby AUY11345303 » Tue Dec 20, 2011 3:58 pm

Langerhans cells are antigen presenting cells and macrophages are phagocytes. They both act in the immune responds. Macrophages are found in the tissue where monocytes(lymphocytes) in the blood, slips it way through into the tissue and differentiate into macrophages. Langerhans cells are found in the stratum spinosum in the epidermis of the skin. I know that langerhans cells are derived from monocytes but do langerhans cells undergo changes and become macrophages?

Hope to see some reply. Thank you. :)
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