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Are STOP codons involved in both TRANSCRIPTION & TRANSLATION

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Are STOP codons involved in both TRANSCRIPTION & TRANSLATION

Postby reyrey389 » Sun Nov 06, 2011 8:02 am

1)Ok, I am really confused about this. Is a "stop codon" used in both transcription and translation.

I have two textbooks one says: "Three of these 64 codons are stop codons that specify the termination of a polypeptide; all the rest code for amino acids" From this textbook I knew this had to do with translation

the other textbook said "Transcription of the DNA strand ends at another special nucleotide sequence called a terminator, which specifies the end of the gene." I think Terminator is another way of saying stop codon here. So yeah this textbook says its involved in transcription.

What do you think? is it involved with transcription, translation, or both?

2) Also one more question, if I'm given the the mRNA strand sequence, UACGCCUAA, and asked to determine the amino acid, would I look at the codon all the way on the left, in the middle, or on the right?
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Postby JackBean » Sun Nov 06, 2011 8:44 am

1) no, terminator is something different than STOP codon. STOP codon is 3-base long and is involved in translation only, terminator is longer and is involved in transcription
2) well, you should first find START codon and then go by 3 AAs at a time

Cis or trans? That's what matters.
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