Question about DNA Replication and Protein Synthesis

[reyrey389]

Do DNA Replication and Protein Synthesis occur at the same time in the cell?

I think that cells produce proteins in ALL phases of the interphase, but I am not too sure.
Anyone have any ideas?

[aptitude]

During the S phase of the cell cycle, rates of protein synthesis are very low. The one exception is the synthesis of histones, of course. Also, during the M phase, microtubule assembly and centrosomal division must occur so tubulin must be rapidly synthesized. Other than that, very little protein synthesis occurs.

[chrisPbacon]

Look at the three stages of Interphase: G1 Stage, S Stage, and G2 Stage. The stages happen in this order, and occur after each stage is fully complete before moving to the next. The G1 stage is where DNA is checked for damage, and if there is damage apoptosis occurs. After the G1 stage the S stage begins. During the S stage, DNA synthesis occurs or "replication". AFTER the S stage, the G2 stage begins and the cell synthesizes proteins to assist in cell division. So following what aptitude said, during the S phase there is no protein synthesis, only DNA replication. The proteins are then used to form microtubules used during the M stage.

However, signal proteins must be present in order for each stage to proceed to the next. So don't confuse these with the synthesis of proteins because they occur outside of the cell, and are received by the plasma membrane.