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Fur color of Himalayan rabbits

Genetics as it applies to evolution, molecular biology, and medical aspects.

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Fur color of Himalayan rabbits

Postby hartfan » Fri Jun 24, 2011 2:09 pm

Hi all, I have a multiple choice problem where I do not understand the official answer.

The Himalayan variety of rabbits has white hair on the body and black hair on the feet, tail, ears and face. The allele for the Himalayan rabbit pigment pattern, c^h, is recessive to the alleles for normal color (all hair agouti), C, as well as dark chinchilla (all hair dark grey), c^chd, and is dominant to the allele for albino (all hair white, no pigment production), c. All of the alleles of this gene produce different versions of the same enzyme involved in pigment production.

A patch of white fur was removed from a Himalayan rabbit and an ice pack secured to the skin. The fur that grew back on the patch was black.

Which of the following about the genotypes of Himalayan rabbits and the explanation for the pigment pattern in Himalayan rabbits is correct?

A. c^h/c^h only; the enzyme is denatured at the high skin temperatures found on the rabbits' bodies
B. c^h/c^h only; the enzyme becomes inactive at the low skin temperatures found on the rabbits' feet, tail, ears and face
C. c^h/c^h and c^h/c only; the enzyme is denatured at the high skin temperatures found on the rabbits' bodies
D. c^h/c^h and c^h/c only; the enzyme becomes inactive at the low skin temperatures found on the rabbits' feet, tail, ears and face


The correct answer is D, while I think if there's an answer that is closest to the right one, it should be C. Can anyone help me think of a reason why D is the correct answer? Thanks.
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Postby JackBean » Mon Nov 07, 2011 5:48 pm

in the beginning, do they mean they have removed really white fur or aguti? Because if it was white, then the one had to be cc.
The only reason I can come up with is that enzymes usually work well with temperatures up to say 40°C, so unless the rabbit has fever, the enzyme should be fine.
http://www.biolib.cz/en/main/

Cis or trans? That's what matters.
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