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need detailed information on the life of mitochondrion

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need detailed information on the life of mitochondrion

Postby mzoltan22 » Tue May 31, 2011 1:14 pm


I want informations such as how it is being built up by the host cell, how it is commanded to enter into certain operational states, how it is partitioned on cell divison, so that both of the dauther cells will get some of them. Mainly, i want to verify a claim wich i read at sens.org (you can also, watch videos by Aubrey de Gray). They say, that one important thing bound to the aging process is the mutation of genes in the mitochondrion (in certain cells i assume) during the lifespan of an individual. These are allegedly mainly (big) deleterious mutations, leading to the mal/disfunction of mitochondrion, causing harm or death to the host cell. That if true, would obviously imply, that there must be some state, when the mitochondrion is not susceptible to such mutations, otherwise, there would be a high probability that malfunctioning mitochondrions would be passed down to offsprings. So i would like to verify that information.

Please give me some answer, or advise a book, where i could find one (or more).
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Postby AKumar » Fri Jun 17, 2011 7:19 pm

Mitochondria don't divide into halves and get into new cells. They have their own set of genes to function...are semi-autonomous. They even have different immune system recognition system which is in may terms related to bacteria. During normal cell division, there may also be duplication and then seggregation of mitochondrial genes, hence the result.
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Postby philipsteele » Sat Jun 18, 2011 6:44 am

Mitochondria imitate much like bacterial cells. So these acquiring of too large, they feel fission. Mitochondrion- powerhouse of the cell- creats ATP-energy Chloroplast- small important.
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Postby JackBean » Thu Dec 15, 2011 3:44 pm

there are many mitochondria in one cell and during the division, they are randomly set between the two new daughter cells. Even if only one mitochondrion was passed to one of the daughter cells, that should be sufficient.

Cis or trans? That's what matters.
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