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How would you know what genotypes to assign for the parents?

Genetics as it applies to evolution, molecular biology, and medical aspects.

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How would you know what genotypes to assign for the parents?

Postby Nivea » Tue Feb 01, 2011 6:13 pm

In humans, cataracts in the eyes and fragility of the bones are caused by dominant alleles that assort independently. A man with cataracts and normal bones marries a woman without cataracts but with fragile bones. The man's father had normal eyes, and the woman's father had normal bones. What is the probability that the first child of this couple will (a) be free from both abnormalities; (b) have cataracts but not have fragile bones; (c) have fragile bones but not have cataracts; (d) have both cataracts and fragile bones?

I would assume the genotype C-ff for parent 1 and ccF- for parent 2. However in the solutions it says parent 1 is Ccff and parent 2 is ccFf
How do you know what genotypes to assign to them? Why isn't the dominant allele as a wild type instead of heterozygous? i.e. CCff instead of Ccff and ccFF instead of ccFf?
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Re: How would you know what genotypes to assign for the parents?

Postby JackBean » Mon Nov 28, 2011 1:21 pm

because of
Nivea wrote:The man's father had normal eyes, and the woman's father had normal bones.
http://www.biolib.cz/en/main/

Cis or trans? That's what matters.
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