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solubility of tripeptides

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solubility of tripeptides

Postby Hudson » Fri Jan 07, 2011 1:37 am

Hey everyone. I'm taking a course online and my tutor is one of those guys that isn't very helpful. I'm having trouble with this question and i'm not sure where to start. How do i recognize if an amino acid or a tripeptide is soluble or not? Im not sure if theres a trick to know by looking at the name of the a.a. or if its just memory work or what? can anyone help? or point me in the right direction. Thanks xoxo

Which of the following tripeptides (only one) would be most likely to be soluble in an organic (hydrophobic) solvent like benzene. Explain.

N - phenylalanine - alanine - glycine – C
N - leucine - alanine - lysine – C
N - proline - phenylalanine - alanine – C
N - arginine - lysine – proline – C
N - glutamine - asparagine - glycine - C
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Postby canalon » Fri Jan 07, 2011 5:30 am

There are tables of aa that are polar (hydrophilic) and those who are non-polar (hydrophobic). Teh more peptides in each category the more the solubility in water will be affected (positively or not).

Good luck for your search.

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Postby JackBean » Fri Jan 07, 2011 7:49 am

since you asking about solubility in hydrophobic solvent, you're looking for peptides with most hydrophobi amino acids (glutamate is not a good choice;) and since it's benzene, it will be even better, if they will be aromatic.

And you need some good guess ;) :)

Cis or trans? That's what matters.
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