plasma membrane & protein orientation

[klapausius]

which of the following statements is true about the orientation of the proteins in the plasma membrane?

(a) the orientation is changed by increasing fluidity of lipids in the bilayer
(b) the orientation is changed by using enzymes that rotate proteins through the lipid bilayer
(c) the orientation is changed by budding and fusing of membrane vesicles
(d) the orientation of membrane proteins cannot be changed

My guess (b)
my thoughts;
(a) increasing fluidity will only affect its location at the non-cystolic leaflet
(c) budding and fusing wont change the orientation, usually be maintained
(d) then we dun need flippase

im not sure whether b) is correct though

[JackBean]

flippase is for lipids, not for proteins, IMHO d is correct

[klapausius]

thanx appreaciate it!

[MrMistery]

jackbean is right. the orientation of a protein is established when it is inserted into the membrane of the ER, and can never be changed

[lehua768]

jackbean is right. the orientation of a protein is established when it is inserted into the membrane of the ER, and can never be changed
"As a biologist, I firmly believe that when you're dead, you're dead. Except for what you live behind in history. That's the only afterlife" - J. Craig Venter