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Benzoic acid and Ascorbic acid on enzymes

Discussion of all aspects of biological molecules, biochemical processes and laboratory procedures in the field.

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Benzoic acid and Ascorbic acid on enzymes

Postby JTeighty » Tue Mar 02, 2010 9:12 pm

Hi,

How does benzoic acid inhibit bacterial growth and act as a preservative? Will this have anything to do with the way it acts as an enzyme inhibitor? How does it actually inhibit the enzyme? What is the mechanism? Is it the same for Ascorbic acid?

Thanks

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Postby JackBean » Tue Mar 02, 2010 10:13 pm

go to http://www.brenda-enzymes.org/index.php4
you can look for the inhibitors and stuff
http://www.biolib.cz/en/main/

Cis or trans? That's what matters.
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Re: Benzoic acid and Ascorbic acid on enzymes

Postby JTeighty » Wed Mar 03, 2010 8:05 am

Hi,

thanks for the response. I used that website to find out that they do inhibit the enzyme but my question was how do they usually inhibit enzymes? Do they have a sort of mechanism? Eg do they denature the enzymes by deforming the active site?
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Postby JackBean » Wed Mar 03, 2010 3:17 pm

you have references at Brenda, so you can try to look to them ;)

(but I think, that denaturation is not taken as inhibition)
http://www.biolib.cz/en/main/

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Re:

Postby JTeighty » Thu Mar 04, 2010 8:06 am

JackBean wrote:
(but I think, that denaturation is not taken as inhibition)


Thanks. That's a good point.
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