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Hsp70 vs. BiP

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Hsp70 vs. BiP

Postby ryanbarnhill » Mon Mar 01, 2010 1:55 am

Are Hsp70 protein and BiP the same thing?
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Postby JackBean » Mon Mar 01, 2010 3:00 pm

at least you could wrote, what you mean :roll: is that so hard to look to wiki?
http://en.wikipedia.org/wiki/Hsp70
I have no idea, what is BiP
http://www.biolib.cz/en/main/

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Re: Hsp70 vs. BiP

Postby ryanbarnhill » Mon Mar 01, 2010 3:38 pm

sorry, I just sometimes have a hard time trusting wiki... I like to get a 2nd opinion. BiP is a chaperone that normally binds Ire1p, during the unfolded protein response, however, it dissociates form Ire1p so that it can assist in protein folding... I think it's a heat shock protein but I'm not sure.
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Postby JackBean » Mon Mar 01, 2010 3:45 pm

if you don't trust wiki, than go to PubMed.com and look for your words.
But I think, I found something for you:
http://www.ncbi.nlm.nih.gov/pubmed/7988 ... tlesearch4
If it didn't work, look for
Haas IG (1994) BiP (GRP78), an essential hsp70 resident protein in the endoplasmic reticulum.
http://www.biolib.cz/en/main/

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Postby MrMistery » Wed Mar 03, 2010 10:15 pm

Hsp70 is a class of proteins, of which BiP happens to belong to. there are many many more types of Hsp70s other than BiP
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