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protein folding

Discussion of all aspects of cellular structure, physiology and communication.

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protein folding

Postby ryanbarnhill » Wed Feb 24, 2010 10:49 pm

i'm having trouble understanding exactly how chaperones help proteins fold. BiP particularly can anyone recommend a link?
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Postby AndrewPhD » Wed Feb 24, 2010 11:47 pm

The chaperonin creates a hydrophobic environment for the denatured protein to be seperated from the factors that caused it to become denatured. But the chaperonin doesnt actually renature the protein itself.
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Postby JackBean » Thu Feb 25, 2010 7:11 am

again, don't forget the GroEL-GroES complex. It uses bunch of ATP, so this one is for sure active process
http://www.biolib.cz/en/main/

Cis or trans? That's what matters.
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Re: protein folding

Postby ryanbarnhill » Thu Feb 25, 2010 6:16 pm

thanks guys.
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