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Difference between proto-oncogenes and tumor supressor genes

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Difference between proto-oncogenes and tumor supressor genes

Postby Swede » Tue Feb 23, 2010 2:18 pm

What is the difference between proto-oncogenes and tumor supressor genes?

I know that proto-oncogenes when injured or mutated generate oncogenes, whose synthesized proteins lead to neoplasi in different ways. But isn't that the case also for tumor supressor genes? I really don't get the difference.
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Postby david23 » Tue Mar 16, 2010 12:19 am

actually you know what, why dont you tell me what you think the difference between the 2 is
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Postby Darby » Tue Mar 16, 2010 2:12 pm

There is some overlap - a tumor suppressor could be a proto-oncogene.

But not necessarily, and that's the focus of your question. Where do the terms not overlap?
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