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X-linked or autosomal?

Genetics as it applies to evolution, molecular biology, and medical aspects.

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X-linked or autosomal?

Postby mensamedlem » Sun Nov 15, 2009 6:38 pm

How to determine whether a pedigree is x-linked or autosomal?
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Re: X-linked or autosomal?

Postby zami'87. » Mon Nov 16, 2009 5:18 am

At the first glance..X-linked recessive means that some males will be affected if mother is a carrier.None will inherit disorder from father.Trace female line and see if some sons are affected.
Most(or all) women will be healthy in pedigree.
In autosomal recessive disorder there's the same chance that males and females will be affected..as it's recessive disorder it skips generations.
In autosomal dominant disorders you can trace affected individual,there's no skipping,one of his/her parent is affected.
In X dominant males can be affected only if mother is affected..daughter can be affected if either mother or father is affected..

and mitochondrial DNA linked disorders..inherited from mother
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