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Question on filtrate in nephron becoming more concentrated

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Question on filtrate in nephron becoming more concentrated

Postby HannahCo » Wed Oct 07, 2009 1:11 am

Hello everyone! I'm new to this forum but a friend told me about how great you guys are :)

Any ways on to my question..

I am having trouble understanding how the filtrate becomes more concentrated when it goes through the nephron... I don't really understand the process :?

Here's the actual question: Why does the filtrate become more and more concentrated as the liquid flows through the nephron? Explain fully - include the following terms/concepts: passive transport (diffusion and osmosis), water, sodium chloride, urea, anti-diuretic hormone ADH, and glucose
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Postby mith » Fri Oct 16, 2009 5:23 am

well, water flows out but solute stays in, so it becomes more concentrated.
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Postby JackBean » Sat Oct 17, 2009 12:13 am

I don't think so :-P
In my opinion, the whole solution gets out, but solutes get back afterwards, don't they?

(BTW really detailed description :lol: )
http://www.biolib.cz/en/main/

Cis or trans? That's what matters.
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Postby Jokerstyle » Sat Oct 17, 2009 7:38 am

I'll give it a shot, but it would be good if someone could confirm this before OP uses it.

The fluid is first "squeezed" out into the nephron starting at the "Renal Corpuscle". The excreted fluid now starts to travel through the nephron.
At the very beginning, it's basically a huge jumble of all kinds of fluids, including a huge lot of water. (This is called primary urine)

What happens in the nephron is that the body will re-absorb that which it finds neccesary through diffusion and osmosis, and leave waste-products behind, including the harmful urea which is a nitrogen-intense waste formed in the liver.

If the body is dehydrated, it will release extra ADH into the body. ADH simply put makes the body able to re-absorb more water from the primary urine, partly from creating extra water-uptake channels.

Sodium Chloride - I can't remember exactly what this does, but if I were to take a logical guess - I'd say that if you have alot of sodium chloride (salt) in your primary urine it would mean a osmotic pressure would be applied, and more water is likely to return to the neprhon. (Which would cause dehydration)

Anyway, hope this isn't wrong, but as I said, best wait 'til someone confirms it :)

Edit: Oh, and the filtrate becomes more and more concentrated due to the removal of water and such. In theory, all that will remain is urea and salt, and other waste products.
(Imagine you have a glass of lemonade, the lemonade gets stronger the less water in the glass)
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Postby mith » Sat Oct 17, 2009 7:38 pm

you're forgetting the very important purpose of urea in loops of henle.
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Postby jwalin » Mon Oct 26, 2009 10:42 am

aren't the saltstaken up in the reabsorption
yes they are along with glucose.
biohazard covers it all except the last part regarding NaCL.
loops of henle are the specific places for reabsorption
it isn't what you do that matters but it is how you do it
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Postby bellyjelly » Tue Jul 12, 2011 9:20 am

thanks for intersting information...i will tell my teacher....he will be surprised to hear it....
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