The science behind 'the burn'

[Charchar]

There was not much research when I plugged this in to the search engine, so I thought I could come here and speculate. What causes the 'burn' during prolonged strenuous exertion? From my research I found that metabolic processes leave lactate and bradykin, among other substances, waste build up? Is there even on going research in this field? I surprisingly found very little on it. Well, from what I could dig up, I pieced together that this waste build up in the system causes the ph/acidity in the blood to rise and active the Acid Sensing Ion Channel to start firing pain signals. I suppose Im looking for discussion here and maybe leads into more research.

[Darby]

I'm not sure much is known, but the burn may very well be a pain perception rather than a true burn - perhaps like what capsaicins (I've spelled that wrong, I think) from "hot" foods produce.

[mith]

I read a recent article debunking the whole lactic acid claim. Some Cal professor was quoted as saying the lactic acid was being used as a fuel.

[Charchar]

Yes, pain is very subjective. What one person may find unbearable another may think is not that bad. I have seen that article, but its been awhile since I saw it last. I cant remember if it was that article I read, but I remember reading an article that stated it was not lactic acid that was the culprit for the 'burn', but rather a gas that resulted from lactate being metabolized. I was wondering if there was anyway you could inhibit the acid sensing ion channel from being triggered.