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Spleen

Human Anatomy, Physiology, and Medicine. Anything human!

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Postby victor » Fri Jul 08, 2005 7:21 am

Is the RBC means red blood cell?
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Postby opuntia » Fri Jul 08, 2005 7:26 am

That's what i call it ...i don't know about anyone else :lol:
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Postby victor » Fri Jul 08, 2005 7:27 am

Hmm...as long as I know that babies make their RBC in their liver... :roll: then, it move to the bone marrow..
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Postby opuntia » Fri Jul 08, 2005 7:31 am

Actually only toward the end of fetal life, the red blood cells are manufactured in the spleen [ i missed this point in the other post ]
Last edited by opuntia on Fri Jul 08, 2005 7:44 am, edited 1 time in total.
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Postby victor » Fri Jul 08, 2005 7:38 am

Oh..it's fetus....sorry, I didn't pay attention for that..thanks anyway :D
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Postby opuntia » Fri Jul 08, 2005 7:46 am

Well my bio teacher says that fetus and baby are as different as egg and bird :lol:
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Postby victor » Fri Jul 08, 2005 7:56 am

egg and baby bird... :lol:
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Postby Dr.Stein » Fri Jul 08, 2005 2:14 pm

Spleen is a secondary lymphoid organ and also a blood regulation site. A part of spleen that works as secondary lymphoid organ called white pulp, whereas for blood regultion is a part named red pulp.
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Postby Jokkon » Tue Jul 26, 2005 11:50 pm

i thoguth all white blood cells are produced in the red bone marrow? and lymphocytes mature at either the red bone marrow the thymus gland?
does spleen really produce red blood cells?
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Postby b_d_41501 » Wed Jul 27, 2005 1:14 am

All blood cells are produced in the bone marrow. As children, most of our bones produce blood. As we age this gradually diminishes to just the bones of the spine (vertebrae), breastbone (sternum), ribs, pelvis and small parts of the upper arm and leg. Bone marrow that actively produces blood cells is called red marrow, and bone marrow that no longer produces blood cells is called yellow marrow. The process by which the body produces blood is called hematopoiesis.

All blood cells (RBCs, WBCs and platelets) come from the same type of cell, called the pluripotential hematopoietic stem cell. This group of cells has the potential to form any of the different types of blood cells and also to reproduce itself. This cell then forms committed stem cells that will form specific types of blood cells.

During formation, the RBC eventually loses its nucleus and leaves the bone marrow as a reticulocyte. At this point, the reticulocyte contains some remnants of organelles. Eventually these organelles leave the cell and a mature erythrocyte is formed. RBCs last an average of 120 days in the bloodstream. When RBCs age, they are removed by macrophages in the liver and spleen.
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Postby b_d_41501 » Wed Jul 27, 2005 1:18 am

Didn't want to make the first post too long. lol :D

Most WBCs (neutrophils, eosinophils, basophils and monocytes) are formed in the bone marrow. T lymphocytes start in the bone marrow from pluripotent hematopoietic stem cells, then travel to and mature in the thymus gland. The thymus is located in the chest between the heart and sternum (breastbone). B lymphocytes mature in the bone marrow.
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Postby Dr.Stein » Wed Jul 27, 2005 6:40 am

Jokkon wrote:i thoguth all white blood cells are produced in the red bone marrow? and lymphocytes mature at either the red bone marrow the thymus gland?

Yes but lymphocytes are still naïve in those area (primary lymphoid organs). They will undergo maturation in secondary lymphoid organs, e.g. spleen, lymph nodes, tonsil, mucosal, thru exposing to antigens. Then they will proliferate and differentiate into effector cells or regulatory functions.

Jokkon wrote:does spleen really produce red blood cells?

Naah. Spleen just 'recycles' the senescent RBCs, keeping useful components, eliminating useless ones.
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