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Golgi Body

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Golgi Body

Postby Harvey23 » Mon Nov 03, 2008 12:33 pm

Hi there,

Just a quick question on the Golgi Body (assuming maturation model)...

My text book says vesicles fuse with each other and then the cis-cisternae after budding from the rough ER. But what exactly is the cis-cisternae? Purely a collection of vesicles early in the maturation process?...or rather a physically different membrane structure that is always there? What confuses me is that surely the cis-cisternae physically moves as it matures and become the trans-cisternae over time. However if this is true, what do subsequent vesicles budding off the rought ER fuse with?

The same applies for the trans-cisternae. What do the vesicles leave behing after they bud and where does this structure go, assuming it is physically the same structure as the cis-golgi but with different enzymes specific to reactions in the later stages of glycosylation. I dont understand how the maturation model can work without the trans-cisternae being recycled or something at the end of maturation but the text book makes no mention of this.

Hope this makes sense
Harvey :wink:
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Postby HELISA » Sat Nov 22, 2008 9:50 pm

Golgi apparatus even though highly dynamic doesn't dissapear because it's recreated over and over again. Cis-cisternes don't dissapear because even though they move during maturation to medial and trans Golgi, what's left behind them is again recreated from ER vesicles. Similarily, trans-Golgi cisternes don't disappear, because medial Golgi will recreate them. That's how I understand the process...
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