Login

Join for Free!
117037 members


simpleast wya to make animal live longer

Genetics as it applies to evolution, molecular biology, and medical aspects.

Moderator: BioTeam

simpleast wya to make animal live longer

Postby steelcat » Thu Oct 23, 2008 9:10 am

what is the simplest way to make animal live longer
1) knock or copy a special genes
2) extend Telomeres
3) Stem Cell
4)Induced Pluripotent Stem Cell:

I think is (1). because (2) there is no much experiment on extend Telomeres
and. (3) (4) is mostly about regrowing a organ.
steelcat
Garter
Garter
 
Posts: 27
Joined: Fri Sep 05, 2008 12:52 pm

Postby Adamx » Mon Oct 27, 2008 7:10 am

Well, telomere length can indicate mortality risks. A cell's lifespan integrity depends on this, no?
Adamx
Garter
Garter
 
Posts: 4
Joined: Mon Oct 27, 2008 6:26 am

Postby mith » Mon Oct 27, 2008 2:03 pm

The question is simplest, pretty sure 1 is not the simplest.
Living one day at a time;
Enjoying one moment at a time;
Accepting hardships as the pathway to peace;
~Niebuhr
User avatar
mith
Inland Taipan
Inland Taipan
 
Posts: 5345
Joined: Thu Jan 20, 2005 8:14 pm
Location: Nashville, TN


Postby jota13 » Tue Nov 18, 2008 12:20 pm

I think telomeres have the solution, but it's a cellular solution; I don't know if it would work with associations of cells.
jota13
Garter
Garter
 
Posts: 2
Joined: Mon Nov 17, 2008 1:48 pm

Re:

Postby Chumbawamba » Fri Nov 21, 2008 4:03 am

jota13 wrote:I think telomeres have the solution, but it's a cellular solution; I don't know if it would work with associations of cells.

Right, as there are vital organs which don't replicate cells (brain, muscles usually). So preventing telomere shrinking in these vital organs is pointless.
User avatar
Chumbawamba
Garter
Garter
 
Posts: 7
Joined: Mon Nov 17, 2008 3:34 am
Location: Orono, ME

Postby MrMistery » Sat Nov 22, 2008 4:13 am

both muscles and brain cells make cells for their whole lifetime.
The point was that just because you can make an individual cell live longer that does not mean the whole organism will live longer.
"As a biologist, I firmly believe that when you're dead, you're dead. Except for what you live behind in history. That's the only afterlife" - J. Craig Venter
User avatar
MrMistery
Inland Taipan
Inland Taipan
 
Posts: 6832
Joined: Thu Mar 03, 2005 10:18 pm
Location: Romania(small and unimportant country)

Re:

Postby Chumbawamba » Sat Nov 22, 2008 4:38 am

MrMistery wrote:both muscles and brain cells make cells for their whole lifetime.
The point was that just because you can make an individual cell live longer that does not mean the whole organism will live longer.

They do? I always thought they never did. The rate must not be nearly as high as other cells if they do divide.
User avatar
Chumbawamba
Garter
Garter
 
Posts: 7
Joined: Mon Nov 17, 2008 3:34 am
Location: Orono, ME

Postby MrMistery » Sat Nov 22, 2008 8:44 pm

neurons and adult mucle cells obviously do not divide, but both organs contain stem cells that make new cells through the lifetime of the individual.
"As a biologist, I firmly believe that when you're dead, you're dead. Except for what you live behind in history. That's the only afterlife" - J. Craig Venter
User avatar
MrMistery
Inland Taipan
Inland Taipan
 
Posts: 6832
Joined: Thu Mar 03, 2005 10:18 pm
Location: Romania(small and unimportant country)

Re: simpleast wya to make animal live longer

Postby misterzed » Wed Dec 17, 2008 3:27 am

There has been some work recently suggesting restriction of calorie intake can increase life expectancy.*

http://www.newscientist.com/article/dn8950-cutting-calories-may-boost-your-lifespan.html

Its also been tested in rats with some interesting results

And in one study the lifespan of yeast has been extended 1000% using the same method.

*Though obviously keeping an animal on the brink of starvation its entire life isn't going to have positive effects on its quality of life, so not exactly something recommendable.
misterzed
Garter
Garter
 
Posts: 3
Joined: Mon Dec 15, 2008 11:07 am


Return to Genetics

Who is online

Users browsing this forum: No registered users and 1 guest

cron