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database of small molecule and receptor targets

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database of small molecule and receptor targets

Postby simplitia » Thu Jul 03, 2008 8:33 pm

Dear all:
I am wondering if there is a database/index that has a list of molecules and their receptor targets? Basically it would look something like:
drug123 targets gene345

thanks and advance! :D

Alex
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Postby dipjyoti » Sat Jul 05, 2008 10:51 am

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Re: database of small molecule and receptor targets

Postby pdavis68 » Sun Sep 07, 2008 5:17 pm

I'm not aware of any general database for this. It's simply too large a subject for a generalized database to be useful.

The way most people, I believe, determine this information is in looking at a specific target or looking at a specific small molecule.

For example, for drugs, pretty much any serious pharmacology text will tell you what the targets are for those drugs.

On the other hand, if you want to look at targets, it's generally easy to find ligands for them.

Wikipedia is actually a really good place to get started. For example, want to know what ligands target the adrenergic receptors? Simply look it up in wikipedia: http://en.wikipedia.org/wiki/Adrenergic_receptors#Comparison

The problem is, from a usefulness point of view, a generalized database, like what you're asking for, is of limited use. Most people are looking for targets of a specific molecule or ligands for a specific target.

Are you looking for anything in particular?
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Re: database of small molecule and receptor targets

Postby Pratap » Tue Oct 13, 2009 10:27 am

Hi.. i have seen your query today... To my knowledge, there is a product called NetPro which provide manually curated small molecule-protein interactions. They have more that 50K unique small molecules covering more than 100K interactions. Quite reliable.

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Postby ainala8055 » Tue Oct 13, 2009 10:53 am

Datbases such as DrugBank database,Cambridge database
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