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M i c r o v i l l i Question

Human Anatomy, Physiology, and Medicine. Anything human!

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M i c r o v i l l i Question

Postby lilyspetal » Fri Jan 18, 2008 1:41 am

Can someone provide an in depth explanation of microvili's function? Do they operate to increase cell surface area as needed and why would cell surface area need to increase? Thanks.
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Postby Revenged » Sun Jan 20, 2008 12:10 pm

disarracharide enzymes (i.e. maltase and sucrase) are produced only on the villi of the small intestine...

you need them to produce single sugar units - glucose, fructose - that can be taken up by diffusion/active transport into the bloodstream...

no villi occurs in coeliac disease - where gluten causes an autoimmune reaction to destroy the tissue... you get pretty much constant diarrhoea if you don't stick to a gluten free diet...
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Postby MrMistery » Sun Jan 20, 2008 4:04 pm

the cell surface area needs to increase in order for absorption to take place at a high enough rate. A protein transporter can only work so fast...
More about how microvilli form here:http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=mboc4.figgrp.3025
"As a biologist, I firmly believe that when you're dead, you're dead. Except for what you live behind in history. That's the only afterlife" - J. Craig Venter
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Postby Darby » Tue Jan 22, 2008 3:26 am

There's so much more membrane on a microvilli-covered surface; if materials are moving across that surface, in or out, they'll move faster.
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